منابع مشابه
Metabolism of trichloroethylene.
A major focus in the study of metabolism and disposition of trichloroethylene (TCE) is to identify metabolites that can be used reliably to assess flux through the various pathways of TCE metabolism and to identify those metabolites that are causally associated with toxic responses. Another important issue involves delineation of sex- and species-dependent differences in biotransformation pathw...
متن کاملMetabolism of trichloroethylene and tetrachloroethylene in human subjects.
A linear correlation exists between the trichloroethylene concentration in the work environments and the level of total trichloro compounds in the urine of the workers, as expressed by the equation: Gamma = 7.25=chi + 5.5, where Gamma is trichloroethylene in air (ppm) is Chi is total trichloro compounds in urine (mg/l). Trichloroethanol level is also linearly related to trichloroethylene concen...
متن کاملTrichloroethylene (TCE)
Current evaluation Conclusion from the previous Monograph: Trichloroethylene (TCE) is probably carcinogenic to humans (Group 2A) based on limited evidence in humans for the carcinogenicity of TCE and sufficient evidence in experimental animals for the carcinogenicity of TCE. In making the overall evaluation, the Working Group considered the following evidence: (i) although the hypothesis linkin...
متن کامل[Trichloroethylene poisoning].
Trichloroethylene and trichloroethanol were given intraperitoneally to guinea-pigs. Their effects were tested by measuring the threshold current intensity of electrical skin stimulation, the electrical excitability of the motor cerebral cortex, by recording and analysis of the electroencephalogram, and by electrocardiographic examination. The two compounds had similar effects on the nervous sys...
متن کاملExposure assessment of trichloroethylene.
This article reviews exposure information available for trichloroethylene (TCE) and assesses the magnitude of human exposure. The primary sources releasing TCE into the environment are metal cleaning and degreasing operations. Releases occur into all media but mostly into the air due to its volatility. It is also moderately soluble in water and can leach from soils into groundwater. TCE has com...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 2000
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.00108s2177